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In experiments of other receptor tyrosine kinases implicated inside the oncogenesis of GIST, nilotinib obtained potent and selective inhibition of PDGFR? and PDGFR?. As is the case with imatinib, nilotinib potently inhibited the autophosphorylation of A31 cells transformed by PDGFRAVancomycin was initial isolated in 1953, by Edmund Kornfeld (Operat… Read More

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